I have pulled apart a few engines before and none wore as well as this one I ran exclusively on synthetic, I forget the exact one but it was a full syn penrite 10w 50 or something.
I bought the engine with some 80,000 on it, it had 400,000 when I parted it and I abused it every chance I got, worst of it was WOT out the driveway in -2 to -4 winter mornings with no warm up.
The crank was virtually like new, shinny and smooth with no noticeable scratches under the nail or finger , measured up as new and so I kept it as a spare. Bearing were also great, they looked like less than 100k of use from other engines I have pulled apart and I honestly though the engine was going to be trashed from the amount of Ks and abuse it got but turned out to be one of the best ones I ever took apart. Equally as good was my mates VY motor at 355,000 which also had next to no wear either. He used synthetic only as well, Castrol edge.
On my engine I have had a used oil analysis done and it showed negligible wear metals so I stuck to the oil I used since it was working so well, also the analysis showed the the anti wear and other additives to be spot on to what penrite claimed.
Only disadvantages I found is becasue of the smaller on average and uniform molecular sizes they do end up finding more seals to leak through and also oil consumption become somewhat noticeable where with mineral it's negligible leaks and consumption. But its anti wear abilities I think it's superior especially in harsher operating conditions due to being able to maintain a film and stable viscosity under a much wider range of temps and pressures.
Also note how clean the engine is, that's 400k on the clock. With anything you get what you pay for. Of course there is always marketing hype but if you stick to the upper mid range of any product you are mostly going to be ensured you get good quality for a reasonable price. It's the 2 extremes of the price range where you get stung, That including top of the line and bottom of the barrel, mineral now days is bottom of the barrel and is priced accordingly so.
I'm the director of VSH (Vlad's Spec Holden), because HSV were doing it ass about.